Dopamine Advantage 30 vegetarian capsules Numer katalogowy: 02413 What Is Dopamine Advantage? Our innovative formula supports motivation and focus, thanks to a combination of phellodendron bark powder and a special neurologically active form of vitamin B12. Together, these nutrients protect your brain cells from cellular stress and encourage healthy dopamine levels, promoting concentration and helping you stay focused on your task at hand. Benefits at a Glance: Helps maintain youthful dopamine levels Helps stay sharp & motivated Promotes healthy cognitive function Maintaining healthy dopamine levels Dopamine is a neurotransmitter or brain chemical that’s produced in your brain and released into synaptic clefts, the microscopic spaces between your neurons, to relay signaling information from one neuron to the next. Unfortunately, factors such as nutrition, aging, environmental changes and stress can cause a decline in dopamine levels, affecting cognitive performance, motivation and can even lead to a wide variety of health issues. Both of the nutrients in our brain-friendly formula maintain youthful dopamine levels in the brain by actively binding to enzymes that binds to and breaks down dopamine, by inhibiting these enzymes’ activity, there’s more dopamine available to the brain. Phellodendron bark and MAO-B Phellodendron amurense, commonly known as amur cork tree, has many health benefits, including neuroprotective properties. In a detailed 2016 screening study, Phellodendron amurense ranked as one of the most potent extracts for inhibiting the activity of monoamine oxidase-B (MAO-B), an enzyme involved in the metabolism of dopamine.1 Adenosylcobalamin and LRRK2 Adenosylcobalamin is a neurologically active form of vitamin B12—it can cross the brain-blood barrier and it’s more readily available to the brain. A 2019 study showed vitamin B12 also protects the brain from oxidative stress and that it modulates Leucine-Rich Repeat Kinase 2’s (LRRK2) activity, an enzyme that regulates dopamine levels.2-4  Supplement Facts Serving Size 1 vegetarian capsule Amount per serving: Vitamin B12 (as adenosylcobalamin) 500 mcg Phellodendron (bark) powder 500 mg Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silica                                                                   Gluten free Non-GMO Vegetarian Dosage and Use Take one (1) capsule daily, or as recommended by a healthcare practitioner. Warnings KEEP OUT OF REACH OF CHILDREN DO NOT EXCEED RECOMMENDED DOSE Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. + References European J Med Plants. 2016,15(1) The Neuroscientist. 2018,24(5):486-500. Frontiers in neuroscience. 2020,14:527-527. Cell Res. 2019,29(4):313-329.