One-Per-Day Tablets 60 tablets Item Catalog Number: 02313 Our One-Per-Day multivitamin provides the same essential vitamins, minerals, and other nutrients as our Two-Per-Day formula, in a single convenient dose. This is important because Recommended Dietary Allowances (or RDAs) provide protect you from deficiency. But for optimal health support, you need the ideal dose of high-quality vitamins and minerals every day. Our Formula Beats Centrum® 10 ways* 50 times more vitamin B1 25 times more vitamin B6 12 times more vitamin B12 10 times more biotin 10 times more selenium 8 times more vitamin C 2.5 times more vitamin B3 2 times more vitamin D 3 times more vitamin E 2 times more zinc *Formula compared to Centrum® Silver® Adults 50+. Vitamin D for healthy minds and bodies We all know vitamin D supports bone health. But vitamin D also promotes healthy cell division, supports immune system health, and more.2,3 Because of widespread vitamin D deficiency, nutritional scientists are calling for an increased vitamin D intake: 1,000 IU per day and higher. Our One-Per-Day multivitamin delivers 2,000 IU of vitamin D3 with every serving. Vitamin C for immune health, arterial health, and more Vitamin C is famously associated with immune system health, an effect that may result from its ability to scavenge free radicals and protect against oxidative stress, as well its stimulation of the production and function of white blood cells.4-6 Additionally, vitamin C is vital to collagen formation, the connective tissue found throughout healthy arterial walls, skin, bones, and teeth.5 Our One-Per-Day formula delivers 470 mg of vitamin C per serving. B Vitamins help maintain youthful metabolism Your body needs B vitamins to release energy stored in carbohydrates, fats, and proteins — energy your cells use to carry out their daily functions. But there’s more than one “vitamin B.” And because they are metabolically codependent, B vitamins work together to keep you healthy. That’s why our formula contains readily metabolized forms of vitamin B1, riboflavin (B2), vitamin B12, vitamin B6, and more. Bioactive 5-MTHF Folate Our One-Per-Day formula now contains 5-methyltetrahydrofolate (5-MTHF), a form of folate that is up to seven times more bioavailable than folic acid.7 This is particularly important for those with certain genetic enzyme deficiencies, since 5-MTHF is already in a metabolically active form.8 High-potency minerals, antioxidants, and extracts A multivitamin is not complete without the minerals and other nutrients essential to healthy living. Our One-Per-Day formula provides 10 times more biotin and twice as much zinc as Centrum® Silver® Adults 50+. Our formula also delivers 100 mg of magnesium and 150 mcg of iodine, as well as trace minerals like manganese and boron. Alpha-lipoic acid — Alpha-lipoic acid is a potent defender against oxidative stress that promotes metabolic and nerve health, and helps protect vitamin C and glutathione against damaging free radicals.10-12 Selenium — Selenium supports heart and brain health, promotes a healthy inflammatory and immune response, helps quench free radical activity.13,4 Our One-Per-Day formula has three unique forms of selenium (200 mcg total): SelenoExcell®,SelenoPure®, Se-methyl L-selenocysteine, and sodium selenite, each form acting along a different biological pathway. Apigenin — This powerful botanical bioflavonoid is found in many fruits and vegetables.15 Apigenin helps boost the body’s natural cellular defenses. Marigold extract — Standardized for both trans-lutein and trans-zeaxanthin, the marigold extract in our One-Per-Day formula promotes ocular health and helps inhibit oxidative stress. Supplement Facts Serving Size 1 tablet Amount Per Serving Vitamin A (as beta-carotene) (5000 IU) 1500 mcg Vitamin C (as ascorbic acid, calcium and niacinamide ascorbates) 470 mg Vitamin D3 (as cholecalciferol) (2,000 IU) 50 mcg Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol) 67 mg Thiamine (vitamin B1) (as thiamine HCl) 75 mg Riboflavin (vitamin B2) (as riboflavin, riboflavin 5’-phosphate) 50 mg Niacin (as niacinamide,niacinamide ascorbate) 50 mg Vitamin B6 ((as pyridoxine HCl, pyridoxal 5’-phosphate) 75 mg Folate (as L-5-methyltetrahydrofolate calcium salt) 680 mcg Vitamin B12 (as methylcobalamin) 300 mcg Biotin 300 mcg Pantothenic acid Folate (as D-calcium pantothenate) 50 mg Iodine (as potassium iodide) 150 mcg Magnesium (as magnesium oxide) 100 mg Zinc (as zinc citrate, L-OptiZinc® zinc mono-L-methionine sulfate) 25 mg Selenium [as sodium selenite, SelenoExcell® high selenium yeast, SelenoPure® L-selenomethionine] 200 mcg Manganese (as manganese citrate, gluconate) 2 mg Chromium [as Crominex® 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit] 200 mcg Molybdenum (as molybdenum amino acid chelate) 100 mcg Inositol 50 mg Alpha lipoic acid 25 mg Natural mixed tocopherols (providing gamma, delta, alpha, beta) 20 mg Bio-Quercetin phytosome (providing 5 mg quercetin [from Japanese sophora concentrate (flower bud)], phosphatidylcholine complex [from sunflower]) 15 mg Marigold extract (flower) [std. to 5 mg trans-lutein, 155 mcg trans-zeaxanthin] 11.12 mg Apigenin 5 mg Boron (as boron amino acid chelate) 3 mg Lycopene [from LycoBeads® natural tomato extract (fruit)] 1 mg Other ingredients: microcrystalline cellulose, stearic acid, croscarmellose sodium, starch, maltodextrin, dicalcium phosphate, vegetable stearate, silica, aqueous film coating (purified water, hydroxypropyl methylcellulose, glycerin). Lycored Lycopene™ is a registered trademark of Lycored, Orange, New Jersey. SelenoExcell® is a registered trademark of Cypress Systems Inc. L-OptiZinc® and logo are trademarks of Lonza or its affiliates. SelenoPure® is a trademark of Nutrition 21. Dosage and Use Take one (1) tablet daily with meals, or as recommended by a healthcare practitioner. Caution Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels. Warnings KEEP OUT OF REACH OF CHILDREN DO NOT EXCEED RECOMMENDED DOSE Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. Int J Diabetes Dev Ctries. 2010,30(3):153-161 J Bone Miner Res. 2004 Aug,19(8):1221-30. J Bone Miner Res. 2006 Mar,21(3):397-405. Bone. 2008 May,42(5):996-1003. Steroids. 2001 Mar-May,66(3-5):375-80. Bone. 2006 Oct,39(4):946-53. Am J Clin Nutr. 2008 Aug,88(2):513S-519S. J Clin Endocrinol Metab. 2004 Jan,89(1):76-80. Am J Prev Med. 2011 Jul,41(1):68-74. Proc Nutr Soc. 2012 Feb,71(1):50-61. Med Hypotheses. 2011 Dec,77(6):1145-7. Dermatoendocrinol. 2011 Jan,3(1):11-7. Mol Cancer. 2011 May 18,10:58. J Invest Dermatol. 2012 Dec,132(12):2762-9. Anticancer Res. 2012 Jan,32(1):223-36. Biol Blood Marrow Transplant. 2015 Sep,21(9):1627-31. Endocr Metab Immune Disord Drug Targets. 2015 Jul 1. [Epub ahead of print] Nutrients. 2015 Jul 27,7(8):6088-108. Biochim Biophys Acta. 2012 Dec,1826(2):443-57. Redox Rep. 2010,15(1):11-9. Adv Nutr. 2011 Mar,2(2):78-88. Altern Med Rev. 2003 Nov,8(4):359-77. J Invest Dermatol. 2002 Apr,118(4):565-72. Radiat Environ Biophys. 2007 Mar,46(1):61-8. Free Radic Biol Med. 2007 Sep 1,43(5):853-9. PLoS Negl Trop Dis. 2012,6(7):e1729. Indian J Physiol Pharmacol. 2014 Oct-Dec,58(4):371-5. Basic Clin Pharmacol Toxicol. 2015 Apr 21. doi: 10.1111/bcpt.12413. [Epub ahead of print] Am J Clin Nutr. 2003 Jan,77(1):189-95. Ann N Y Acad Sci. 1980,355:80-97. Pharm Res. 2010 Jun, 27(6): 962-78. Linus Pauling Institute, 2012. http://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid Accessed 4/25/2018 Inflamm Res. 2017 Nov, 66(11): 947-959.